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Showing posts from March, 2021

How Live Attenuated Vaccines stimulates immunity?

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Attached to MHC class II antigens, The APCs recirculate and display fragments of the processed antigen on their cell surface. This complex of processed foreign antigen peptide and host MHC class II antigens form an area of the precise signal, with which APCs (along with the MHC peptide complex) triggers the activation of T-helper lymphocytes. Once they replicate within the host live, attenuated vaccines stimulate protective immune responses. Digested by scavenger cells, the antigen-presenting cells (APCs) that circulate throughout the body, the host are released into the extracellular space surrounding the infected cells and the viral proteins produced within and are then acquired, internalized . B cells, which work together to expand immune response, these APCs include macrophages, dendritic cells. These complexes together are recognized by a second class of T cells, in conjunction with other stimulation by APCs and production of cytokine-stimulated T cells, killer or cytotoxic c...

What is Acute Postinfectious Glomerulonephritis?

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Acute postinfectious glomerulonephritis could also be a kidney disease that follows after an infection. The foremost common and best understood kind of acute postinfectious glomerulonephritis is poststreptococcal glomerulonephritis . Less is known about the other kinds of postinfectious glomerulonephritis. Deep abscesses, and infected atrioventricular shunts in hydrocephalus, additionally, there are glomerulonephritides that occur during persistent bacterial infections like bacterial endocarditis. An outsized number of bacterial, viral, and mycotic infections could even be followed by acute glomerulonephritis. Especially after bacterial and viral infections, a proliferative kind of glomerulonephritis occurs. With generally a worse prognosis, in parasitic infections membranous or membranoproliferative forms are seen more often. However, most cases of acute postinfectious glomerulonephritis are caused by A streptococci and follow upper airway infections , like pharyngitis or tonsilliti...

Why precision Medicine?

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To increase patient specificity is a major goal of modern medicine so the right treatment is administered at the right time in the right dose to the right patient. For example, in the area of oncology, treatment methods are moving away from one-size-fits-all approaches. To target those specific alterations knowing the unique molecular mutations driving a person’s condition allows us to design therapies. Integrate information derived from various tests pathologists today must be able to and correlate it with clinical information. Increasingly with precision medicine, pathologists will need to leave the laboratory and play a more active role in clinical decision-making at the bedside. The need for pathologists to work more closely with clinicians is the new frontier of medicine. Interactions between pathologists and the patient care team should increase in future. A pathologist in a Taiwan said: “Clinicians shall offer the first-line clinical information should be offered to the c...